A bug’s life in the gut and why we need chips to understand it

Hi there! Welcome to our residence, welcome to your gut. As you can see it’s crowded in here. We’re living together with hundreds of different kinds of bacteria, fungi, and other microorganisms. Together, you can call us your ‘intestinal microbiome’. You might wonder...

A Recipe for Organ-on-Chip Fabrication, by a Biologist

For successful Organ-on-Chip research, combining multiple areas of expertise is crucial. Even though there is constant feedback from one to the other discipline, in practice, they are very different: a biologist spends most of the day nourishing and photographing...

Jens Puschhof successfully defended his thesis

Today, NOCI researcher Jens Puschhof from the Hubrecht Institute, group of Prof. Hans Clevers, defended his thesis with cum laude honors. Thesis titled “Investigations on epithelial biology using organoid differentiation and co-cultures: Building representative models...

How close can we come to the human?

How close can we come to the human? Article review: Gut-brain axis interaction in Parkinson’s disease and the accuracy of recreating human physiology in model systems In the NOCI, one of our head missions is to make complex human tissue and organ systems in...